Visual Rehabilitation in Laryngo-Onycho-Cutaneous (LOC) Syndrome
نویسندگان
چکیده
منابع مشابه
Laryngo-onycho-cutaneous (LOC) syndrome; Long Term Outcomes of Two Patients with laryngeal Involvement
LOC syndrome has been recently represented as a subtype of junctional epidermolysis bullosa (JEB) with autosomal recessive genetic aberration. LOC syndrome presents with distinguished skin and mucous membranes excessive granulation tissue formation that may lead to delayed wound healing, laryngeal airway obstruction and visual impairment which will result in blindness. So far, most cases are co...
متن کاملLaryngo-onycho-cutaneous syndrome: an inherited epithelial defect.
Three children with an unusual but clearly defined combination of clinical findings that appear to have been inherited in an autosomal recessive manner are described. All had developed laryngeal abnormalities, chronic skin ulceration, nail dystrophy, and conjunctival disease in infancy. In every case, dental enamel was hypoplastic and both skin and mucosal surfaces demonstrated increased suscep...
متن کاملAggressive periodontitis in a young Pakistani female with laryngo-onycho-cutaneous syndrome.
The periodontal status of patients with laryngo-onycho-cutaneous syndrome is unknown. This study describes a case of severe aggressive periodontitis in a 19-year-old American-Pakistani female with laryngo-onycho-cutaneous syndrome. The patient showed abundant dental plaque and calculus accumulations, suppuration and hemorrhage from virtually all gingivae and interdental papillae, and extensive ...
متن کاملAn unusual N-terminal deletion of the laminin alpha3a isoform leads to the chronic granulation tissue disorder laryngo-onycho-cutaneous syndrome.
Laryngo-onycho-cutaneous (LOC or Shabbir) syndrome (OMIM 245660) is an autosomal recessive epithelial disorder confined to the Punjabi Muslim population. The condition is characterized by cutaneous erosions, nail dystrophy and exuberant vascular granulation tissue in certain epithelia, especially conjunctiva and larynx. Genome-wide homozygosity mapping localized the gene to a 2 Mb region on chr...
متن کاملFollow up of patients with ocular scarring secondary to LOC syndrome treated by amniotic membrane transplantation.
AIMS To document and discuss the long term outcome of a new ophthalmic treatment for laryngo-onycho-cutaneous (LOC) syndrome. METHODS Two children were treated by excision of ocular granulation tissue and ocular surface rehabilitation with frozen amniotic membrane (AM). The clinical course of both patients was followed and documented at 2 years and 4 years following the surgery. RESULTS Pat...
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ژورنال
عنوان ژورنال: Advances in Ophthalmology & Visual System
سال: 2014
ISSN: 2377-4290
DOI: 10.15406/aovs.2014.01.00018